Biomimetic Composite Materials
Our tissues are composed of composite materials of biopolymers and ceramic structures, with hierarchical order for guiding cell and tissue organization. Using micro- and nano- fabrication techniques we design and develop composite biomaterials that recapitulate these architectures.
Cell and Tissue Engineering
Cell state in tissue is ruled by a multivariate presentation of signals that orchestrate diverse forms and functions. Using hydrogel microengineering and 3D bioprinting technology, we are exploring how biochemical, biophysical, and biological cues in the cell and tissue microenvironment orchestrate cell state, matrix synthesis, and hierarchical assembly.
Biofabrication and Microphysiological Engineering
Animal models fail to accurately mimic human biology and disease progression. We leverage our cell and biomaterials engineering to build reproducible microscale tissues and organoids using human cells, with formats amenable to plate- and chip-based assays to aid fundamental studies and drug development.
Cell-based Product Manufacture
Commercialization and clinical translation of cell-based products require materials and infrastructure that are scalable and translatable to good manufacturing practice (GMP). We work with industry and clinical partners to optimize biomaterials, bioreactors, and process analytics, for the reproducible production of cells, tissues and biologics.
Recent news
We publish news about the latest changes, announcements, and recent projects
Selected Publications
