Biomimetic Composite Materials Overview
Our tissues are composed of composite materials of biopolymers and ceramic structures, with hierarchical order for guiding cell and tissue organization. Using micro- and nano- fabrication techniques we design and develop composite biomaterials that recapitulate these architectures.
- Representative publications
- Junmin Lee, Amr A. Abdeen, Jamila Hedhli, Kathryn L. Wycislo, Iwona Dobrucka, Timothy M. Fan, Lawrence W. Dobrucki, and Kristopher A. Kilian, Melanoma topology reveals a stem-like phenotype that promotes angiogenesis, Science Advances, 2017, 3(10), e1701350
- Amr A. Abdeen, Jared B. Weiss, Junmin Lee, and Kristopher A. Kilian, Matrix composition and mechanics directs pro-angiogenic signaling from mesenchymal stem cells, Tissue Engineering, Part A, 2014, 20 (19-20), 2737-2745.
- Junmin Lee, Amr A. Abdeen, Douglas Zhang, and Kristopher A. Kilian, Directing stem cell fate on hydrogel substrates by controlling cell geometry, matrix mechanics and adhesion ligand composition, Biomaterials, 2013, 34, 8140-814