Cell-based Product Manufacture Project Details
Commercialization and clinical translation of cell-based products require materials and infrastructure that are scalable and translatable to good manufacturing practice (GMP). We work with industry and clinical partners to optimize biomaterials, bioreactors, and process analytics, for the reproducible production of cells, tissues and biologics.
- Representative publications
- Douglas Zhang, Junmin Lee, Michael B. Sun, Yi Pei, James Chu, Martha U. Gillette, Timothy M. Fan, and Kristopher A. Kilian, Combinatorial discovery of defined substrates that promote a stem cell state in malignant melanoma, ACS Central Science, 2017, 3 (5), 381-393
- Junmin Lee, Amr A. Abdeen, Kathryn L. Wycislo, Timothy M. Fan, and Kristopher A. Kilian, Interfacial geometry dictates cancer cell tumorigenicity, Nature Materials, 2016, 15, 856-862
- Joshua M. Grolman, Douglas Zhang, Andrew M. Smith, Jeffrey S. Moore, and Kristopher A. Kilian, Rapid 3D extrusion of synthetic tumor microenvironments, Advanced Materials, 2015, 27 (37), 5512-5517