Timeline

Publications

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Advancing Synthetic Hydrogels through Nature-Inspired Materials Chemistry

Adv. Mater. 2024, 2404235. Bram G. Soliman, Ashley K. Nguyen, J. Justin Gooding, Kristopher A. Kilian
2023
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Photocrosslinked Silk Fibroin Microgel Scaffolds for Biomedical Applications

Adv. Funct. Mater. 2024; 2313354F. Karimi, N. Farbehi, F. Ziaee, K. Lau, M. Monfared, M. Kordanovski, H. Joukhdar, T. G. Molly, R. Nordon, K. A. Kilian, M. H. Stenzel, K. S. Lim, J. Rnjak-Kovacina
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ROS-mediated anticancer effects of EGFR-targeted nanoceria

J Biomed Mater Res.2023; 1-16Kochurani K. Johnson, Pramod Koshy, Chantal Kopecky, Michelle Devadason, Joanna Biazik, Xiaoran Zheng, Yue Jiang, Xiaochun Wang, Yiling Liu, Jeff Holst, Jia-Lin Yang, Kristopher A. Kilian, Charles C. Sorrell
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Theranostic Activity of Ceria-Based Nanoparticles toward Parental and Metastatic Melanoma:2D vs 3D Models

ACS Biomaterials Science & Engineering 2023 9 (2), 1053-1065Kochurani K. Johnson, Chantal Kopecky, Pramod Koshy, Yiling Liu, Michelle Devadason, Jeff Holst, Kristopher A. Kilian, and Charles C. Sorrell
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Hierarchical assembly of tryptophan zipper peptides into stress-relaxing bioactive hydrogels

Nat Commun 2023, 14, 6604Ashley K. Nguyen, Thomas G. Molley, Egi Kardia, Sylvia Ganda, Sudip Chakraborty, Sharon L. Wong, Juanfang Ruan, Bethany E. Yee, Jitendra Mata, Abhishek Vijayan, Naresh Kumar, Richard D. Tilley, Shafagh A. Waters & Kristopher A. Kilian
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Magnetic Nanofibrous Hydrogels for Dynamic Control of Stem Cell Differentiation

ACS Appl. Mater. Interfaces 2023, XXXX, XXX, XXX-XXXMd Shariful Islam, Thomas G.Molley, Tzong-tyng Hung, C. I. Sathish, Vina D. L. Putra, Gagan K. Jalandhra, Jake Ireland, Yancheng Li,Jiabao Yi,Jamie J. Kruzic, and Kristopher A. Kilian
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Engineered Biomaterials for Developing the Next Generation of In Vitro Tumor Models

Guest Editorial – Special Issue: Engineered Biomaterials for Developing the Next Generation of In Vitro Tumor Models
Adv. Healthcare Mater. 2023, 12: 2300411Kristopher Kilian, Claudia Fischbach, Eliza Li Shan Fong
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Evaluation of the Immune Response to Chitosan-graft-poly(caprolactone) Biopolymer Scaffolds

ACS Biomater. Sci. Eng. 2023, XXXX, XXX, XXX-XXXMatthew J. Moore, Yuen Ting Lam, Miguel Santos, Richard P. Tan, Nianji Yang, Juichien Hung, Zihao Li, Kristopher A. Kilian, Jelena Rnjak-Kovacina, Johannes B. Pitts, Henning Menzel, and Steven G. Wise
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Gas-modulating microcapsules for spatiotemporal control of hypoxia

Proceedings of the National Academy of Sciences 2023, 120(16) e2217557120Thomas G. Molley, Shouyuan Jiang, Louis Ong, Chantal Kopecky, Chavinya D. Ranaweera, Gagan K. Jalandhra, Laura Milton, Egi Kardia, Zeheng Zhou, Jelena Rnjak-Kovacina, Shafagh A. Waters, Yi-Chin Toh, and Kristopher A. Kilian
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Electrostatic Assembly of Multiarm PEG-Based Hydrogels as Extracellular Matrix Mimics: Cell Response in the Presence and Absence of RGD Cell Adhesive Ligands

ACS Biomater. Sci. Eng. Article ASAPPanthipa Suwannakot, Stephanie Nemec, Newton Gil Peres, Eric Y. Du, Kristopher A. Kilian, Katharina Gaus, Maria Kavallaris, and J. Justin Gooding
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In situ formation of osteochondral interfaces through “bone-ink” printing in tailored microgel suspensions

#Invited article – Special Issue on Biofabrication for orthopedic, maxillofacial, and dental applications
Acta biomaterialia 2023, 156, 75-87 Gagan K. Jalandhra, Thomas G. Molley, Tzong-tyng Hung, Iman Roohani, Kristopher A. Kilian
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Defined microenvironments trigger in vitro gastrulation in human pluripotent stem cells

Advanced Science 2023, 10, 5, 2203614Pallavi Srivastava, Sara Romanazzo, Chantal Kopecky, Stephanie Nemec, Jake Ireland, Thomas G. Molley, Kang Lin, Pavithra Jayathilaka1, Elvis Pandzic, Avani Yeola, Vashe Chandrakanthan, John Pimanda, Kristopher Kilian
2022
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Cell-laden gradient microgel suspensions for spatial control of differentiation during biofabrication

#Invited article – Special Issue on Biofabrication Applications
Adv. Healthcare Mater. 2022, 11 (24), 2201122 Thomas G. Molley, Tzong-tyng Hung, Kristopher A. Kilian
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Hydrogel Microtumor Arrays to Evaluate Nanotherapeutics

Adv. Healthcare Mater. 2022, 2201696 Yiling Liu, Stephanie Nemec, Chantal Kopecky, Martina Stenzel, Kristopher A Kilian
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Biomaterials directed activation of a cryostable therapeutic secretome in induced pluripotent stem cell derived mesenchymal stromal cells

Journal of Tissue Engineering and Regenerative Medicine 2022 In Press Sara Romanazzo, Chantal Kopecky, Shouyuan Jiang, Riddhesh Doshi, Vipul Mukund, Pallavi Srivastava, Jelena Rnjak-Kovacina, Kilian Kelly, Kristopher A. Kilian
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Production of Antibacterial Activity and Bone Cell Proliferation by Surface Engineering of Ga- or Mn-Doped Ceria-Coated Biomedical Titanium Alloy

Adv. Eng. Mater. 2022, 2200077 Ayda Khosravanihaghighi, Pramod Koshy, Muhammad Yasir, Sara Romanazzo, Vedran Lovric, Kristopher Alan Kilian, Mark Duncan Willcox, William Robert Walsh, Charles Christopher Sorrell
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A tunable tumor microenvironment through recombinant bacterial collagen-hyaluronic acid hydrogels

#Invited article – Special Issue on Self-Assembling Biomaterials from Proteins, Peptides, and DNA
ACS Appl. Bio Mater. 2022, 5 (10), 4581-4588 Stephanie Nemec, Sylvia Ganda, Karrar Al Taief, Chantal Kopecky, Rhiannon Kuchel, Hélène Lebhar, Christopher P. Marquis, Pall Thordarson, Kristopher A. Kilian
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Gallium Nanodroplets are Anti-Inflammatory without Interfering with Iron Homeostasis

ACS Nano 2022, 16 (6), 8891-8903 Chengchen Zhang, Biyao Yang, Joanna M. Biazik, Richard F. Webster, Wanjie Xie, Jianbo Tang, Francois-Marie Allioux, Roozbeh Abbasi, Maedehsadat Mousavi, Ewa M. Goldys, Kristopher A. Kilian, Rona Chandrawati, Dorna Esrafilzadeh, and Kourosh Kalantar-Zadeh
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Structural aspects controlling the mechanical and biological properties of tough, double network hydrogels

Acta Biomaterialia 2022, 138, 301-312 Yuwan Huang, Pavithra B. Jayathilaka, Md. Shariful Islam, Carina B. Tanaka, Meredith N. Silberstein, Kristopher A. Kilian, Jamie J Kruzic
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Force-mediated molecule release from double network hydrogels

Chem. Commun. 2021, 57, 8484 - 8487 Pavithra Jayathilaka, Thomas Molley, Yuwan Huang, Shariful Islam, Michael R Buche, Meredith Silberstein, Jamie J. Kruzic and Kristopher Kilian
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Pluripotent stem cell derived mesenchymoangioblasts improve cardiac function and vascularity after myocardial infarction

Cytotherapy 2021, 23, 12, 1074-1084Sujitha Thavapalachandran, Thi Yen Loan Le, Sara Romanazzo, Fairooj N.Rashid, Masahito Ogawa, Kristopher A.Kilian, Paula Brown, Jim Pouliopoulos, Anthony M.Barry, Peter Fahmy, Kilian Kelly, Eddy Kizana, James J.H.Chong
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Antibody Self-Assembly Maximizes Cytoplasmic Immunostaining Accuracy of Compact Quantum Dots

Chemistry of Materials, 2021, 33, 13, 4877–4889 Ma, Liang; Geng, Junlong; Kolossov, Vladimir; Han, Zhiyuan; Pei, Yi; Lim, Sung Jun; Kilian, Kristopher; Smith, Andrew
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Heterotypic tumor models through freeform printing into photostabilized granular microgels

Biomaterials Science 2021, 9, 4496-4509 Thomas Molley, Gagan Jalandhra, Stephanie R Nemec, Aleczandria S Tiffany, Amrutha Patkunarajah, Kate Poole, Brendan Harley, Tzong-Tyng Hung, Kristopher Kilian
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Interfacial curvature in confined co-culture directs stromal cell activity with spatial corralling of pancreatic cancer cells

Advanced Biology 2021, 5: 2170064 Stephanie Nemec, Joey Lam, Jingxiao Zhong, Celine Heu, Paul Timpson, Qing Li, Janet Youkhana, George Sharbeen, Phoebe A. Phillips, Kristopher A. Kilian*
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Synthetic Bone‐Like Structures Through Omnidirectional Ceramic Bioprinting in Cell Suspensions

Advanced Functional Materials, 2021, 2008216 Sara Romanazzo, Thomas Gregory Molley, Stephanie Nemec, Kang Lin, Rakib Sheikh, John Justin Gooding, Boyang Wan, Qing Li, Kristopher Alan Kilian, Iman Roohani
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Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine Induced multipotent stem cells from human adipocytes

Science Advances, Vol. 7, no. 3, eabd1929 Avani Yeola, Shruthi Subramanian, Rema A. Oliver, Christine A. Lucas, Julie A. I. Thoms, Feng Yan, Jake Olivier, Diego Chacon, Melinda L. Tursky, Pallavi Srivastava, Jason R. Potas, Tzongtyng Hung, Carl Power, Philip Hardy, David D. Ma, Kristopher A. Kilian, Joshua McCarroll, Maria Kavallaris, Luke B. Hesson, Dominik Beck, David J. Curtis, Jason W.H. Wong, Edna C. Hardeman, William R. Walsh, Ralph Mobbs, Vashe Chandrakanthan and John E. Pimanda
2020
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Freeform printing of heterotypic tumor models within cell-laden microgel matrices

Biorxiv, preprint Thomas G. Molley, Gagan K. Jalandhra, Stephanie R. Nemec, Aleczandria S. Tiffany, Brendan A. C. Harley, Tzong-tyng Hung, Kristopher A. Kilian
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Geometric regulation of histone state directs melanoma reprogramming

Commun Biol 3, 341 2020 Junmin Lee, Thomas G. Molley, Christopher H. Seward, Amr A. Abdeen, Huimin Zhang, Xiaochun Wang, Hetvi Gandhi, Jia-Lin Yang, Katharina Gaus, Kristopher A. Kilian
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Geometrically Structured Microtumors in 3D Hydrogel Matrices

Advanced Biosystems, 2020, 4, 2000056 Molley, Thomas G.; Wang, Xiaochun; Hung, Tzong-tyng, Jayathilaka, Pavithra B.; Yang, Jia-lin; Kilian, Kristopher A.
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Porous chitosan adhesives with L-DOPA for enhanced photochemical tissue bonding

Acta Biomaterialia, 2020, 101, 314-326 Ruprai, Herleen; Shanu, Anu; Mawad, Damia; Hook, James M.; Kilian, Kristopher; George, Laurel; Wuhrer, Dr. Richard ; Houang, Jessica ; Ta, Daniel; Myers, Simon ; Lauto, Antonio
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The structural fate of lipid nanoparticles in the extracellular matrix

Materials Horizons, 2020,7, 125-134 Sarith R. Bandara, Thomas G. Molley, Hojun Kim, Priyalini A. Bharath, Kristopher A. Kilian, Cecilia Leal
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Porous Chitosan Films Supports Stem Cells and Facilitates Sutureless Tissue Repair

ACS Applied Materials & Interfaces, 2019, 11, 36, 32613–32622 Ruprai, Herleen; Romanazzo, Sara; Ireland, Jake; Kilian, Kristopher; Mawad, Damia; George, Laurel; Wuhrer, Dr. Richard ; Houang, Jessica ; Ta, Daniel; Myers, Simon ; Lauto, Antonio
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Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions

Nature Communications, 2019, 10:909 Phuong Le, Sung Jun Lim, Brian C. Baculis, Hee Jung Chung, Kristopher A. Kilian & Andrew M. Smith
2018
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Vertical integration of cell-laden hydrogels with bioinspired photonic crystal membranes

Advanced Materials Interfaces, 2018, vol: 5 (23) pp: 1870115 Yi Pei, Sayyed Hamed Shahoei, Yanfen Li, Peter Reece, Erik R. Nelson, J. Justin Gooding, Kristopher A Kilian
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Surveillance of Cancer Stem Cell Plasticity Using an Isoform-Selective Fluorescent Probe for Aldehyde Dehydrogenase 1A1

ACS Cent. Sci., 2018, 4 (8), pp 1045–1055 Chelsea Anorma, Jamila Hedhli, Thomas E. Bearrood, Nicholas W. Pino, Sarah H. Gardner, Hiroshi Inaba, Pamela Zhang, Yanfen L, Daven Feng, Sara E. Dibrell, Kristopher A. Kilian, Lawrence W. Dobrucki, Timothy M. Fan, and Jefferson Chan
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Simultaneous cell traction and growth measurements using light

Journal of Biophotonics, 2018, e201800182 Shamira Sridharan, Yanfen Li, Louis Foucard, Hassaan Majee, Basanta Bhaduri, Alex Levine, Kristopher Kilian, Gabriel Popescu
2017
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Melanoma topology reveals a stem-like phenotype that promotes angiogenesis

Science Advances, 2017, 3(10), e1701350Junmin Lee, Amr A. Abdeen, Jamila Hedhli, Kathryn L. Wycislo, Iwona Dobrucka, Timothy M. Fan, Lawrence W. Dobrucki, and Kristopher A. Kilian
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Multimodal Assessment of Mesenchymal Stem Cell Therapy for Diabetic Vascular Complications

Theranostics, 2017, 7(16), 3876-3888 Jamila Hedhlia, Christian J. Konopka, Sarah Schuh, Hannah Bouvin, John A. Cole, Heather Huntsman, Kristopher Killian, Iwona T. Dobrucki, Marni Boppart, Lawrence W. Dobruckia
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Anti-inflammatory ω-3 endocannabinoid epoxides

Proceedings of the National Academy of Sciences, 2017, 114 (30), E6034-E6043 Daniel R. McDougle, Amr Abdeen, Raymond Adili, Megan Caputo, John Krapf, Rodney Johnson, Kristopher Kilian, Michael Holinstat, and Aditi Das
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Combinatorial discovery of defined substrates that promote a stem cell state in malignant melanoma

ACS Central Science, 2017, 3 (5), 381-393 Douglas Zhang, Junmin Lee, Michael B. Sun, Yi Pei, James Chu, Martha U. Gillette, Timothy M. Fan, and Kristopher A. Kilian
2016
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Epidermal mechano-acoustic sensing electronics for cardiovascular diagnostics and human-machine interfaces

Science Advances, 2016, 2 (11), e1601185 Yonggang Huang,Yuhao Liu, James J. S. Norton, Raza Qazi, Zhanan Zou, Kaitlyn R. Ammann, Hank Liu, Lingqing Yan, Phat L. Tran, Kyung-In Jang, Jungwoo Lee, Douglas Zhang, Kristopher A. Kilian, Sung Hee Jung, Timothy Bretl, Jianliang Xiao, Marvin J. Slepian, Jae-Woong Jeong, and John A. Rogers
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Magnetoactive hydrogels for temporal modulation of stem cell activity

Advanced Healthcare Materials, 2016, 5 (19), 2536-2544 Amr A. Abdeen, Junmin Lee, N. Ashwin Bharadwaj, Randy H. Ewoldt, and Kristopher A. Kilian
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Reforming an Undergraduate Materials Science Curriculum with Computational Modules

Journal of Materials Education, 2016, 38 (3-4), 161-174 Rachael Mansbach, Andrew L. Ferguson, Kristopher A. Kilian, Jessica A. Krogstad, Cecilia Leal, André Schleife, Dallas R. Trinkle, Matthew West, and Geoffrey L. Herman
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Mechanochemical functionalization of disulfide linked hydrogels

Materials Horizons, 2016, 3, 447-451 Junmin Lee, Meredith N. Silberstein, Amr A. Abdeen, Sang Yup Kim, and Kristopher A. Kilian
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Interfacial geometry dictates cancer cell tumorigenicity

Nature Materials, 2016, 15, 856-862 Junmin Lee, Amr A. Abdeen, Kathryn L. Wycislo, Timothy M. Fan, and Kristopher A. Kilian
2015
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Mimicking the Extracellular Matrix : The Intersection of Matrix Biology and Biomaterials

Gregory A. Hudalla and William L. Murphy, RSC, Cambridge, UK, pgs. 161-194 (2015) Kristopher A. Kilian, Biomaterials: Incorporating ECM-Derived Molecular Features Into Biomaterials (book chapter)
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Rapid 3D extrusion of synthetic tumor microenvironments

Advanced Materials, 2015, 27 (37), 5512-5517 Joshua M. Grolman, Douglas Zhang, Andrew M. Smith, Jeffrey S. Moore, and Kristopher A. Kilian
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Biofunctionalization of free-standing porous silicon films for self-assembly of photonic devices

Soft Matter, 2012, 8, 360-366 Till Böcking, Kristopher A. Kilian, Peter J. Reece, Katharina Gaus, Michael Gal and J. Justin Gooding
2011
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Spacing of integrin ligands influences signal transduction in endothelial cells

Biophysical Journal, 2011, 101, 764-773Guillaume Le Saux, Astrid Magenau, Krishanthi Gunaratnam, Kristopher A. Kilian, Till Böcking, Justin Gooding and Katharina Gaus
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Mesoporous silicon photonic crystal microparticles: towards single-cell optical biosensors

Faraday Discussions, 2011, 149, 301-317 Bin Guan, Astrid Magenau, Krisopher A. Kilian, Simone Ciampi, Katharina Gaus, Peter J. Reece and J. Justin Gooding
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Substrate independent assembly of optical structures guided by biomolecular interactions

ACS Applied Materials & Interfaces, 2010, 2 (11), 3270-3275 Till Böcking, Kristopher A. Kilian, Peter J. Reece, Katharina Gaus, Michael Gal and J. Justin Gooding
2009
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Smart tissue culture: in situ monitoring of cellular secretion with nanostructured photonic crystals

Nano Letters, 2009, 9 (5), 2021-2025Kristopher A. Kilian, Leo M. H. Lai, Astrid Megenau, Sian Cartland, Till Böcking, Katharina Gaus, Nick Di Giorlamo, Michael Gal, and J. Justin Gooding
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Silicon-based mesoporous photonic crystals: towards single cell optical biosensors

Proceedings of the SPIE, 2009, 739703, 1-8 Kristopher A. Kilian, Astrid Magenau, Till Böcking, Katharina Gaus, Michael Gal, and J. Justin Gooding
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Organic modification of mesoporous silicon rugate filters: the influence of nanoarchitecture on optical behaviour

International Journal of Nanotechnology, 2008, 5 (2), 170-178 Kristopher A. Kilian, Till Böcking, Leo M. H. Lai, Suhrawardi Ilyas, Katharina Gaus, Michael Gal, and J. Justin Gooding
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Click-Chemistry in Mesoporous Materials: Functionalization of Porous Silicon Rugate Filters

Langmuir, 2008, 24 (11), 5888-5892 Simone Ciampi, Till Böcking, Kristopher A. Kilian, Jason Harper, J. Justin Gooding
2007
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Peptide Modified Optical Filters for Detecting Protease Activity

ACS Nano, 2007, 1 (4), 355-361 Kristopher A. Kilian, Till Böcking, Katharina Gaus, Michael Gal, and J. Justin Gooding
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Forming Antifouling Organic Multilayers on Porous Silicon Rugate Filters towards in vivo/ex vivo Biophotonic Devices

Advanced Functional Materials, 2007, 17 (15), 2884-2890 Kristopher A. Kilian, Till Böcking, Suhrawardi Ilyas, Katharina Gaus, Wendy Jessup, Michael Gal, and J. Justin Gooding
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Functionalization of Acetylene-Terminated Monolayers on Si(100) Surfaces: A Click Chemistry Approach

Langmuir, 2007, 23 (18), 9320-9329 Simone Ciampi, Till Böcking, Kristopher A. Kilian, Michael James, Jason Harper, J. Justin Gooding
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Porous silicon based narrow line-width rugate filters

Optical Materials, 2007, 29, 619-622 S. Ilyas, T. Böcking, K. Kilian, P.J. Reece, J. Gooding, K. Gaus and M. Gal
2004
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Production of Complex Nucleic Acid Libraries Using Highly Parallel in situ Oligonucleotide Synthesis

Nature Methods, 2004, 1 (3), 241-248 Michele Cleary, Kristopher Kilian, Yanqun Wang, Jeff Bradshaw, Guy Cavet, Wei Ge, Amit Kulkarni, Patrick J. Paddison, Kenneth Chang, Nihar Sheth, Eric Leproust, Ernest M. Coffey, Julja Burchard, W. Richard McCombie, Peter Linsley and Gregory J. Hannon
2003
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Effects of Atmospheric Ozone on Microarray Data Quality

Analytical Chemistry, 2003, 75 (17), 4672-4675 Thomas L. Fare, Ernest M. Coffey, Hongyue Dai, Yudong D. He, Deborah A. Kessler, Kristopher A. Kilian, John E. Koch, Eric LeProust, Matthew J. Marton, Michael R. Meyer, Roland B. Stoughton, George Y. Tokiwa, and Yanqun Wang