Biography
- Jake received his bachelor degree from Swansea University in Medical Genetics in 2015. He then received his Master’s in Tissue Engineering & Regenerative Medicine from the University of Manchester in 2016. Jake’s Masters research focused on the development and electrophysiological analysis of a 3D cardiac model produced from zebrafish larvae. Jake is currently exploring how topographical structures effect the electrical conductivity of the human heart as a PhD candidate in the Kilian Laboratory at UNSW.
Jake’s a very entrepreneurial individual who has developed an artisan leather business that he runs in his spare time with his partner Jess, visit their store at bearsleatherco.com.au
Contact : jake.ireland@student.unsw.edu.au
Websites:
bearsleatherco.com.au
jakeireland.info
Projects
- Extracellular matrix array and the effects on iPSC calcium handling.
- Topographical patterning of cardiomyocytes.
- The bio-functionalization of organic electrochemical transistors to be used as a cardiac patch.
- Preconditioning of iPSC to develop improved cardiac progenitor cells.
- Electromagnetic influenced mechanical stimulation of cardiomyocytes.
- Utilisation of machine learning to establish parameters of cardiomyocyte contraction metrics from primary cells of different linages.
Publications
- Srivastava P, Romanazzo S, Ireland J, Nemec S, Molley TG, Jayathilaka P, Pandzic E, Yeola A, Chandrakanthan V, Pimanda J, Kilian K., 2021. Defined microenvironments trigger in vitro gastrulation in human pluripotent stem cells. bioRxiv; DOI: 10.1101/2021.10.28.466327
- Hodgson, P., .Ireland, J., Grunow, B., 2018. Fish, the better model in human heart research? Zebrafish Heart aggregates as a 3D spontaneously cardiomyogenic in vitro model system. Progress in Biophysics and Molecular Biology
- Ruprai, H., Romanazzo, S., Ireland, J., Kilian, K., Mawad, D., George, L., Wuhrer, R., Houang, J., Ta, D., Myers, S., Lauto, A., 2019. Porous Chitosan Films Support Stem Cells and Facilitate Sutureless Tissue Repair. ACS Appl. Mater. Interfaces 11, 32613–32622.
- Zeglio, E., Ireland, J., Wang, Y., Travaglini, L. Yue, W., Micholich, A., Lauto, A., Kilian, K., Herland, A., Mawad, D., 2020. Bio-functionalized organic electrochemical transistors. Wiley (In Preperation). in Submission
